Trusted Research Environment – Quark Bioinformatics Platform

Trusted Research Environment (TRE)

Federate. Collaborate. Innovate.

Safeguard Collaborative Clinicogenomics Research Through

Federated Data Analysis.

Designed for healthcare and research organisations, our Trusted Research Environment (TRE) offers a robust platform for federated clinicogenomics data sharing & analysis, enabling full data governance while facilitating seamless research collaboration.

Federated Data Sharing with No Data Movement

Secure Data Access & Analysis for Seamless Collaboration

Full Data Governance & Control for Custodians & Administrators

Federated Data Sharing

Bring your analysis to where the data resides
Securely share data across different projects & users without data ever leaving custodian infrastructure
Enforce a unified data view across geographies, without moving data
Adhere to stringent data privacy & security standards while facilitating collaborative research

Secure Data Access

Offer curated datasets from various data sources through a central catalog
Restrict access to data through fine grained access controls
Enforce Data Access Committee approval workflows for data access requests
Leverage auto scanning for vulnerabilities and Approval Workflows for data uploads & downloads
Preserve data privacy with Data Anonymization

Scalable Self-Service Compute

Leverage pre-built catalogs of popular workflows/pipelines (e.g. RNA-seq) for performing secondary analysis
Avail 1-click workflow/pipeline execution with scalable, on-demand infrastructure provisioning
Bring your own workflows/pipelines
Perform any downstream analyses in Secure Workstations
Leverage Approval Workflows & fine grained access controls

Interoperable Data

Leverage OMOP as a common data model (CDM) to enhance data interoperability
Avail automatic conversion of clinical datasets to OMOP CDM
Avail genomic CDM data mapping for paired data analysis
Experience easy & expedited search & collaboration between multiple parties

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Data Never Leaves Custodian Infrastructure

Our TREs ensure safe, secure & federated sharing of large multi-source datasets with internal & external collaborators.

Biobanks

With our TREs, biobanks are ensured:

Full data governance & provenance

Robust controls over data access

Maximised data impact while adhering to the highest compliance & security standards

Research Instituions

Data silos are unified on a single TRE,

enabling secure interdepartmental & inter-university collaborations.

Researchers may leverage OMOP CDM standardised data to perform large-scale, cross-cohort analyses across disease subtypes.

Biopharma

With our TREs, pharmas can,

Perform large-scale distributed analysis on datasets standardised to a CDM.

Leverage federated analysis to train AI/ML models on de-identified clinicogenomics data &

Accelerate drug discovery pipelines.

Fine-Grained Access Controls

Streamline & secure TRE operations through robust admin controls. Effortlessly control infrastructure offered to research teams.

Manage & Control Costs

Allocate fine grained budgets and centrally control usage across projects & teams. Gain cost visibility of all resources of your TRE.

Robust Admin Controls

Enforce data access controls through metadata management for datasets
Offer curated & secure catalog of Workstations & Workflows/Pipelines to researchers with fine grained access controls
Create custom organization structure and configure fine grained budgets (e.g. Project, Department, User level budgets)
Track costs in real-time to gain visibility into infrastructure usage
Audit trails to track actions performed in the platform

Security & Compliance

Enforce Role Based Access Controls
Platform deployment within customer’s Virtual Private Cloud
Data Encryption at-rest and in-transit
Fine grained Identity & Access Management Policies
Active Directory (AD) / LDAP integration for Single Sign On
Enforce Approval Workflows for all requests

Learn, Connect, and Innovate

Recent Articles

Decoding Epigenomic Patterns with Quark

Epigenetics focuses on gene expression patterns independent of DNA sequences, notably through cytosine methylation. Understanding the methylome enhances insights into cellular functions, cancers, and aging. Quark simplifies methyl-seq data analysis, ensuring robust and reproducible results, essential for precision medicine and integrative analysis, while addressing complexity in interpretation and visualization.

Understanding Conserved Patterns by Leveraging scRNA-seq Integration

Single-cell RNA sequencing (scRNA-seq) enhances understanding of cellular heterogeneity, pivotal for cancer research. However, challenges like batch effects and data complexity hinder analysis. Quark provides an end-to-end solution through horizontal integration, facilitating robust comparative analyses, accelerating insights, and enhancing workflow accessibility, crucial for effective biomarker discovery and precision medicine.

Accelerating Proteomics Research for Biomarker Discovery in Clinical Applications

Proteomics is the comprehensive study of proteins in an organism that uncovers their dynamic roles and complexities. It aids biomarker discovery for diseases, improving drug development and treatment monitoring. Despite analytical challenges, advancements in mass spectrometry and platforms like Quark simplify data analysis, enabling researchers to identify and interpret crucial protein-related insights effectively.

Super charge your scientists today!